A discovery in Little Rock could help the immune system keep fighting solid tumours

CAR T-cell therapy — re-engineering a patient's own immune cells to hunt cancer — works wonders in blood cancers but often falters in solid tumours, where the cells grow exhausted and stop killing. A team at the University of Arkansas for Medical Sciences, led by Sydnye Shuttleworth and senior author Brian Koss, has published findings in Cell, one of the world's top journals, that could help those engineered cells keep their strength for longer. It is early, laboratory-stage science — but every working cancer immunotherapy began exactly here, with someone figuring out why the fighters tire.

SDG 3 · Good health and well-being — Mechanism: tech innovation