Immunotherapy keeps working in the lymph nodes melanoma reaches — reshaping the immune neighbourhood there

When melanoma spreads, it often travels first to nearby lymph nodes — the immune system's local stations. A Mayo Clinic study published in Communications Biology found that checkpoint immunotherapy, a treatment that releases the brakes on immune cells, reshapes the immune environment inside those nodes rather than simply switching off once the cancer arrives. That insight, from senior author Dr Jessica Lancaster's team, could help explain why the drugs work — and how to make them work for more people.

SDG 3 · Good health and well-being — Mechanism: tech innovation