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The cell's recycling trucks have a switch — scientists just found who flips it

Your cells run a constant recycling service: receptors and transport proteins are collected, sorted and sent back out for reuse instead of being rebuilt from scratch. At the University of Basel, a team led by Anne Spang with first author Jachen Solinger has found the switch that loads the right cargo for that return trip — a small protein called ARF-1 working with partners AP-1 and FERARI in a quick 'kiss-and-run' handoff. Published in the Journal of Cell Biology, the mechanism appears in roundworms, yeast and mammal cells alike, suggesting evolution has kept it for a very long time. When the switch was jammed on or off, recycling slowed. 'Cells don't reinvent the wheel every time,' says Spang — they reuse good ideas, and now we can see one of them clearly.

The upbeat factora tiny switch, kept by evolution for hundreds of millions of years, finally caught in the act of keeping our cells tidy.
✓ Verified · Phys.org · 2026-10-19 · Switzerland
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