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For the deepest acne scars, a two-step treatment in Berlin is smoothing what one treatment couldn't

Severe acne can leave deep, tethered scars that resist standard care. Dermatology researchers at Charité in Berlin tested a combination approach: first subcision, a procedure that releases the fibrous bands pulling a scar down, followed by an injectable gel (a polynucleotide preparation) that supports the skin as it rebuilds. In their study, published in a peer-reviewed dermatology journal and reported this week, patients treated with the combination showed meaningful improvement in scar depth and skin texture compared with subcision alone. It is careful, incremental medicine — no miracle, just a better pairing of two existing tools, tested properly, for people whose scars are a daily reminder they'd rather not carry.

The upbeat factorscars are small on a chart and large in a life — a rigorously tested pairing that genuinely softens them is real progress.
✓ Verified · Medical Xpress · 2026-10-29 · Germany
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