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A protein's flicker could tell doctors which breast cancers will outsmart a standard drug — before treatment starts

Researchers at the Garvan Institute of Medical Research in Australia built a living sensor that lights up when a protein called CDK1 is active inside breast cancer cells — CDK1 is the 'engine' cells need to divide. In samples from more than 400 patients, the engine ran hotter as cancers grew more aggressive. That flicker could one day help doctors predict which tumours will resist a widely used class of drugs and choose a better plan sooner. The study is published in Advanced Science.

The upbeat factorwatching cancer's engine glow in real time could spare patients months on a treatment that was never going to work.
✓ Verified · Medical Xpress (Garvan Institute, Advanced Science) · 2026-10-30 · Australia
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