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An old painkiller, given before surgery, may help the body mop up cancer cells that escape

When surgeons remove a tumour, a few cancer cells can already have slipped away — too tiny to see, but able to seed new tumours later. Researchers at Emory University and Beth Israel Deaconess Medical Center asked whether a familiar painkiller could help the immune system catch those escapees. In mouse experiments published in the Journal of Clinical Investigation, giving ketorolac — a common anti-inflammatory painkiller in the same family as ibuprofen — before surgery helped the animals' immune cells control scattered cancer deposits and improved long-term survival. Timing was everything: given after the operation, it did not help. Adding low-dose aspirin and omega-3 compounds strengthened the effect further. This is animal research, not a treatment for people — ketorolac has real side effects, and human trials must come first — but it points to a promising idea: the hours around surgery may be a window when the body's defences can be helped to finish the job.

The upbeat factora cheap, familiar medicine might turn the riskiest hours of cancer surgery into the body's best chance to catch what escaped.
✓ Verified · Knowridge (Emory University, Journal of Clinical Investigation) · 2026-11-01 · USA
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